Photoacoustic wavefront shaping with a long coherence length laser

Maxim N. Cherkashin; Benjamin Keenlyside; Thomas J. Allen; Paul C. Beard; James A. Guggenheim

doi:10.1117/12.2652242

9 March 2023 Photoacoustic wavefront shaping with a long coherence length laser

Maxim N. Cherkashin, Benjamin Keenlyside, Thomas J. Allen, Paul C. Beard, James A. Guggenheim

Proceedings Volume 12379, Photons Plus Ultrasound: Imaging and Sensing 2023; 1237913 (2023) https://doi.org/10.1117/12.2652242
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Photoacoustic (PA) wavefront shaping (WS; PAWS) could allow focusing light deep in biological tissue. This could enable increasing the penetration depth of biomedical optical techniques including PA imaging. However, focussing at depth requires a light source of long coherence length (CL), presenting a challenge because the CLs of typical PA excitation lasers are short. To address this challenge, we developed a PAWS system based on an externally modulated external cavity laser with a long CL. The system was demonstrated by focussing light through rigid scattering media using both PAWS and optical WS. PAWS enabled focussing through diffusers with 8 × enhancements, while all-optical WS enabled focussing through various scattering media including a 5.8 mm thick tissue phantom. By enabling PAWS with increased coherence, the system could facilitate exploring the practical depth limits of PAWS, paving the way to focussing light deep in tissue.

Citation Download Citation

Maxim N. Cherkashin, Benjamin Keenlyside, Thomas J. Allen, Paul C. Beard, and James A. Guggenheim "Photoacoustic wavefront shaping with a long coherence length laser", Proc. SPIE 12379, Photons Plus Ultrasound: Imaging and Sensing 2023, 1237913 (9 March 2023); https://doi.org/10.1117/12.2652242

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available