Near-infrared II photobiomodulation augments nitric oxide bioavailability via phosphorylation of endothelial nitric oxide synthase (Conference Presentation)

Shinya Yokomizo; Dmitriy N. Atochin; Satoshi Kashiwagi

doi:10.1117/12.2646735

14 March 2023 Near-infrared II photobiomodulation augments nitric oxide bioavailability via phosphorylation of endothelial nitric oxide synthase (Conference Presentation)

Shinya Yokomizo, Dmitriy N. Atochin, Satoshi Kashiwagi

Author Affiliations +

Proceedings Volume 12380, Biophotonics and Immune Responses XVIII; 1238007 (2023) https://doi.org/10.1117/12.2646735
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

There is solid evidence of diverse beneficial effects of the treatment with low-power near-infrared (NIR) light in the NIR I window (630-900 nm). We have demonstrated PBM with NIR-II window (1061-1301 nm) augments the immune response of the vaccine, but other beneficial effects of NIR-II laser have not been fully explored. In this study, we have shown that NIR-II laser enhances bioavailable NO in endothelial cells. Since a hallmark of endothelial dysfunction is suppressed eNOS with concomitant NO deficiency, NIR-II laser technology could be broadly used to restore endothelial NO and treat or prevent cardiovascular diseases.

Conference Presentation

Citation Download Citation

Shinya Yokomizo, Dmitriy N. Atochin, and Satoshi Kashiwagi "Near-infrared II photobiomodulation augments nitric oxide bioavailability via phosphorylation of endothelial nitric oxide synthase (Conference Presentation)", Proc. SPIE 12380, Biophotonics and Immune Responses XVIII, 1238007 (14 March 2023); https://doi.org/10.1117/12.2646735

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KEYWORDS

NOx

Near infrared

Laser applications

Luminescence

Skin

Solids

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