Simultaneous Hb-OCE and compression OCE to measure the biomechanical properties of the cornea in vivo

Achuth Nair; Manmohan Singh; Salavat Aglyamov; Kirill V. Larin

doi:10.1117/12.2660523

15 March 2023 Simultaneous Hb-OCE and compression OCE to measure the biomechanical properties of the cornea in vivo

Achuth Nair, Manmohan Singh, Salavat Aglyamov, Kirill V. Larin

Proceedings Volume 12381, Optical Elastography and Tissue Biomechanics X; 123810E (2023) https://doi.org/10.1117/12.2660523
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Assessing corneal biomechanical properties is useful for the diagnosis of ocular disease and for monitoring therapeutic intervention. Here, we demonstrate how two different forms of elastography can be combined to perform a multimodal biomechanical analysis of the cornea. Heartbeat optical coherence elastography (Hb-OCE) and compression elastography were combined to measure the mechanical properties of rabbit corneas in vivo. The results demonstrate that the difference in corneal stiffness measured by Hb-OCE and compression OCE is statistically insignificant, suggesting that both techniques could potentially be used interchangeably to measure corneal stiffness.

Citation Download Citation

Achuth Nair, Manmohan Singh, Salavat Aglyamov, and Kirill V. Larin "Simultaneous Hb-OCE and compression OCE to measure the biomechanical properties of the cornea in vivo", Proc. SPIE 12381, Optical Elastography and Tissue Biomechanics X, 123810E (15 March 2023); https://doi.org/10.1117/12.2660523

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