We present a rapid approach for the estimation of a wavefront shaping modulation from single-photon (linear) fluorescent sources. The approach uses non-invasive, guide star free feedback.
While estimating a wavefront shaping correction from real tissue samples is a complex time-consuming task, iterative time reversal techniques, previously designed for coherent illumination, carry the potential to reduce this acquisition cost. For that, they assume the desired correction mask is an eigenvector of the tissue transmission operator, and compute it using a small number of power iterations.
Unfortunately, under coherent illumination, this approach can only handle restricted targets.
We extend this idea to incoherent fluorescent targets. We show that the incoherent summation allows the approach to handle a larger family of targets and also accelerates its convergence.
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