Metasurface enhanced infrared spectroscopy using vertical nanostructures

Aditya Mahalanabish; Steven H. Huang; Gennady Shvets

doi:10.1117/12.2650689

16 March 2023 Metasurface enhanced infrared spectroscopy using vertical nanostructures

Aditya Mahalanabish, Steven H. Huang, Gennady Shvets

Proceedings Volume 12391, Label-free Biomedical Imaging and Sensing (LBIS) 2023; 123910H (2023) https://doi.org/10.1117/12.2650689
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Vertical nanostructures have been studied extensively and been reported to induce unique responses in cells, including the formation of clathrin coating and accumulation of actin filament which leads to cell membrane curvature around the nanostructures. In our previous works, we have demonstrated that arrays of plasmonic nanoantenna can be used as effective label free biosensors to study live cells when combined with IR spectroscopy in the reflection mode, known as metasurface enhanced IR spectroscopy (MEIRS). By fabricating these plasmonic metasurfaces on top of silica nanopillars, we demonstrate that we can expand the potential of MEIRS: increased protein IR absorption in the amide band and increased sensitivity of our biosensor to processes involving cellular interaction with vertical nanostructures.

Conference Presentation

Citation Download Citation

Aditya Mahalanabish, Steven H. Huang, and Gennady Shvets "Metasurface enhanced infrared spectroscopy using vertical nanostructures", Proc. SPIE 12391, Label-free Biomedical Imaging and Sensing (LBIS) 2023, 123910H (16 March 2023); https://doi.org/10.1117/12.2650689

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