Terahertz technology for biophotonics: a general overview and recent advances in THz spectroscopy toward biology

Romain Peretti

doi:10.1117/12.2675742

11 August 2023 Terahertz technology for biophotonics: a general overview and recent advances in THz spectroscopy toward biology

Romain Peretti

Author Affiliations +

Proceedings Volume 12622, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials VI; 126220P (2023) https://doi.org/10.1117/12.2675742
Event: SPIE Optical Metrology, 2023, Munich, Germany

Abstract

In this conference, we will discuss the advancements in Terahertz (THz) spectroscopy and imaging regarding biophotonics applications. In recent years, THz technology helped various fields, from fundamental physics to industrial process control. THz spectrometers offer a wide spectrum range and high dynamic range, enabling the analysis of semi-transparent materials and living tissues. THz imaging has shown potential in applications such as cancer detection, diabetes foot syndrome, burn wound analysis, and plant hydration assessment. Spectroscopy in the THz range is particularly promising for studying biological systems, including proteins and their compounds. However, challenges such as the strong absorption of water, temperature stability, and small sample sizes need to be overcome. Techniques like scanning microscopy, integrated photonics, and metallic broadband approaches have been explored to enhance THz analysis. Despite the challenges, THz technology has found industrial applications and efforts are being made to improve data processing and error evaluation. Additionally, a proposed method aims to enhance the resolution of THz systems, making them suitable for gas spectroscopy and the sensing of volatile organic compounds relevant to biology.

Conference Presentation

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Romain Peretti "Terahertz technology for biophotonics: a general overview and recent advances in THz spectroscopy toward biology", Proc. SPIE 12622, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials VI, 126220P (11 August 2023); https://doi.org/10.1117/12.2675742

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