CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume 12627 > Article
Paper
11 August 2023 Wide-field Raman spectral band imaging of tumor lesions in veterinary medicine
Mindaugas Tamošiūnas, Roberts Kadiķis, Mikus Melderis, Romans Maļiks, Diāna Dupļevska, Daira Viškere, Ilze Matīse-van Houtana, Blaž Cugmas
Author Affiliations +
Proceedings Volume 12627, Translational Biophotonics: Diagnostics and Therapeutics III; 1262737 (2023) https://doi.org/10.1117/12.2686917
Event: European Conferences on Biomedical Optics, 2023, Munich, Germany
Abstract
Skin and subcutaneous tumors are common in companion animals, that can be difficult to diagnose and treat. Raman spectroscopy shows high diagnostic accuracy in identifying malignant tumors and benign lipomas in dogs and cats. However, the traditional single-point raster scanning approach is not ideal for a large-field-of-view Raman imaging due to its time-consuming nature when scanning areas larger than a square centimeter. Additionally, focusing the excitation spot can lead to high levels of light fluency (J/cm2), potentially causing damage to tissue biomolecules. Furthermore, the resulting raster-scan image often lacks sufficient spatial resolution to effectively compare it with tissue morphology findings. In this study, we focused on implementing EMCCD camera-based Raman imaging to accurately capture Raman spectral band signatures and overcome autofluorescence interference in veterinary cancer samples ex vivo. By utilizing the tunable band-pass filters set-up, our system enables large-field-of-view imaging of specific Raman bands, such as the 1437 cm-1 band or 1652 cm-1 band in biological tissue, proposing a more efficient, accurate and safe approach for Raman imaging in the veterinary field.
(2023) Published by SPIE. Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Mindaugas Tamošiūnas, Roberts Kadiķis, Mikus Melderis, Romans Maļiks, Diāna Dupļevska, Daira Viškere, Ilze Matīse-van Houtana, and Blaž Cugmas "Wide-field Raman spectral band imaging of tumor lesions in veterinary medicine", Proc. SPIE 12627, Translational Biophotonics: Diagnostics and Therapeutics III, 1262737 (11 August 2023); https://doi.org/10.1117/12.2686917
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 8 PAGES
DOWNLOAD PAPER SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
RIGHTS & PERMISSIONS
Get copyright permission  Get copyright permission on Copyright Marketplace
KEYWORDS
Raman spectroscopy
Tissues
Tunable filters
Tumors
Biological samples
Optical filters
Skin
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top