Silicon photonics ultrahigh-resolution in vivo optoacoustic tomography

Yoav Hazan; Ahiad Levi; Michael Nagli; Amir Rosenthal

doi:10.1117/12.2670088

11 August 2023 Silicon photonics ultrahigh-resolution in vivo optoacoustic tomography

Yoav Hazan, Ahiad Levi, Michael Nagli, Amir Rosenthal

Proceedings Volume 12631, Opto-Acoustic Methods and Applications in Biophotonics VI; 126310K (2023) https://doi.org/10.1117/12.2670088
Event: European Conferences on Biomedical Optics, 2023, Munich, Germany

Abstract

A new ultrasound-detection technology is developed for ultrahigh-resolution optoacoustic tomography and is experimentally demonstrated with bandwidths exceeding 200 MHz and lateral resolutions beyond 20 μm. Our technology is based on an optical resonator fabricated in a silicon-photonics platform, which is coated by a sensitivity-enhancing polymer, which also eliminates the parasitic effect of surface acoustic waves. Further improvement in sensitivity is achieved by a low-noise interferometric setup, which eliminates the effect of laser frequency noise on the measurement. In vivo optoacoustic tomography is performed on a mouse ear, revealing its vasculature at detail that has been previously reserved to optoacoustic microscopy.

Citation Download Citation

Yoav Hazan, Ahiad Levi, Michael Nagli, and Amir Rosenthal "Silicon photonics ultrahigh-resolution in vivo optoacoustic tomography", Proc. SPIE 12631, Opto-Acoustic Methods and Applications in Biophotonics VI, 126310K (11 August 2023); https://doi.org/10.1117/12.2670088

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