Ultrafast volumetric imaging with a spatio-temporal optical coherence tomography (STOC-T) system for monitoring hemodynamics in mouse retinal vessels directly from structural data

Wiktor Kulesza; Maciej Wielgo; Piotr Węgrzyn; Sławomir Tomczewski; Onur Cetinkaya; Katarzyna Kordecka; Anna Galińska; Bartłomiej Bałamut; Egidijus Auksorius; Andrzej Foik; Robert Zawadzki; Maciej Wojtkowski; Dawid Borycki; Andrea Curatolo

doi:10.1117/12.2670568

11 August 2023 Ultrafast volumetric imaging with a spatio-temporal optical coherence tomography (STOC-T) system for monitoring hemodynamics in mouse retinal vessels directly from structural data

Wiktor Kulesza, Maciej Wielgo, Piotr Węgrzyn, Sławomir Tomczewski, Onur Cetinkaya, Katarzyna Kordecka, Anna Galińska, Bartłomiej Bałamut, Egidijus Auksorius, Andrzej Foik, Robert Zawadzki, Maciej Wojtkowski, Dawid Borycki, Andrea Curatolo

Author Affiliations +

Proceedings Volume 12632, Optical Coherence Imaging Techniques and Imaging in Scattering Media V; 126320O (2023) https://doi.org/10.1117/12.2670568
Event: European Conferences on Biomedical Optics, 2023, Munich, Germany

Abstract

We present a novel ultrafast imaging system using Spatio-Temporal Optical Coherence Tomography (STOC-T), capable of acquiring structural images of a mouse retina at a volumetric rate of 112 Hz. A calibrated fundus camera and white-light illumination aid the alignment of the mouse and the adjustment of the focal plane in the mouse retina for the STOC-T image. We extract pulsatile blood flow frequency and other hemodynamic parameters from multiple retinal and choroidal vessels from structural-only OCT images, highlighting the prospects of STOC-T for monitoring retinal hemodynamics in a simple way.

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Wiktor Kulesza, Maciej Wielgo, Piotr Węgrzyn, Sławomir Tomczewski, Onur Cetinkaya, Katarzyna Kordecka, Anna Galińska, Bartłomiej Bałamut, Egidijus Auksorius, Andrzej Foik, Robert Zawadzki, Maciej Wojtkowski, Dawid Borycki, and Andrea Curatolo "Ultrafast volumetric imaging with a spatio-temporal optical coherence tomography (STOC-T) system for monitoring hemodynamics in mouse retinal vessels directly from structural data", Proc. SPIE 12632, Optical Coherence Imaging Techniques and Imaging in Scattering Media V, 126320O (11 August 2023); https://doi.org/10.1117/12.2670568

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