In vivo imaging of choroid by spatio-temporal optical coherence tomography

Kamil Lizewski; Egidijus Auksorius; Piotr Wegrzyn; Slawomir Tomczewski; Dawid Borycki; Mounika Rapolu; Ieva Zickiene; Karolis Adomavicius; Bartosz L. Sikorski; Maciej Wojtkowski

doi:10.1117/12.2670908

11 August 2023 In vivo imaging of choroid by spatio-temporal optical coherence tomography

Kamil Lizewski, Egidijus Auksorius, Piotr Wegrzyn, Slawomir Tomczewski, Dawid Borycki, Mounika Rapolu, Ieva Zickiene, Karolis Adomavicius, Bartosz L. Sikorski, Maciej Wojtkowski

Author Affiliations +

Proceedings Volume 12632, Optical Coherence Imaging Techniques and Imaging in Scattering Media V; 126321J (2023) https://doi.org/10.1117/12.2670908
Event: European Conferences on Biomedical Optics, 2023, Munich, Germany

Abstract

Spatio-Temporal Optical Coherence Tomography (STOC-T) is a new imaging modality that uses light with controlled spatial and temporal coherence. The retinal images acquired with the STOC-T system maintain high resolution in all three dimensions, over the entire thickness of about 700 μm, without mechanical scanning. We have employed known data processing algorithms and developed new ones to handle and process the acquired data sets to produce highly corrected 3D data for retinas over large fields of view. The technology and algorithms used here enabled high transverse resolution imaging of the retina and the choroid at various depths, making the differentiation of morphology visible for the first time within the Sattler’s, Haller’s, and choriocapillaris layers. Visualization of choroidal layers was carried out by using the STOCT angio algorithm. We analyzed the acquired data quantitatively to identify an effective biomarker.

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Kamil Lizewski, Egidijus Auksorius, Piotr Wegrzyn, Slawomir Tomczewski, Dawid Borycki, Mounika Rapolu, Ieva Zickiene, Karolis Adomavicius, Bartosz L. Sikorski, and Maciej Wojtkowski "In vivo imaging of choroid by spatio-temporal optical coherence tomography", Proc. SPIE 12632, Optical Coherence Imaging Techniques and Imaging in Scattering Media V, 126321J (11 August 2023); https://doi.org/10.1117/12.2670908

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