Design of a 1D photonic crystal for cancer detection

Qingyu Zhu; Hossein Alisafaee

doi:10.1117/12.2691604

27 November 2023 Design of a 1D photonic crystal for cancer detection

Qingyu Zhu, Hossein Alisafaee

Proceedings Volume 12770, Optics in Health Care and Biomedical Optics XIII; 127703J (2023) https://doi.org/10.1117/12.2691604
Event: SPIE/COS Photonics Asia, 2023, Beijing, China

Conference Poster

Abstract

Cancer is one of the world’s leading causes of death. Non-invasive, highly sensitive detection of cancer has thus been a crucial area of research. This work presents five theoretical designs of one-dimensional defective photonic crystals for detection of cancerous cells. Proposed designs are modeled theoretically on Matlab using the Transfer Matrix Method. Layer thicknesses in each design are optimized for maximum sensitivity. The designs are evaluated and compared based on sensitivity, quality of defect modes, immunity to fabrication errors in thicknesses, and stability under uncertainties in the sample’s refractive index. Theoretically, the design with structure Air/(TiO2/sample)5/(sample/TiO2) 5/Air has a high sensitivity of 1700 nm/RIU and good tolerance for errors. The proposed biosensor can potentially be used in large-scale cancer detection.

Citation Download Citation

Qingyu Zhu and Hossein Alisafaee "Design of a 1D photonic crystal for cancer detection", Proc. SPIE 12770, Optics in Health Care and Biomedical Optics XIII, 127703J (27 November 2023); https://doi.org/10.1117/12.2691604

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