A multimodal PSOCT-NIRS catheter for ablation of atrial fibrillation

Michael Douglass; Reza Mohammadpour; Gauri Srikumar; Alice Qian; Juan Perez; Jonah Majumder; Christine Hendon; Kenneth R. Laurita; Walter J. Hoyt; Ohad Ziv; Andrew M. Rollins

doi:10.1117/12.3006074

12 March 2024 A multimodal PSOCT-NIRS catheter for ablation of atrial fibrillation

Michael Douglass, Reza Mohammadpour, Gauri Srikumar, Alice Qian, Juan Perez, Jonah Majumder, Christine Hendon, Kenneth R. Laurita, Walter J. Hoyt, Ohad Ziv, Andrew M. Rollins

Author Affiliations +

Proceedings Volume 12834, Multimodal Biomedical Imaging XIX; 1283407 (2024) https://doi.org/10.1117/12.3006074
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Atrial fibrillation is a global epidemic linked to millions of deaths each year. One increasingly relevant treatment for the disease is catheter ablation. In this procedure, an electrophysiologist burns lesions to isolate pathogenic tissue in the pulmonary veins from initiating an ectopic heartbeat. Long term efficacy of the procedure still needs to improve. Current intraprocedural feedback does not allow the clinician to properly visualize individual lesions. We developed an integrated polarization sensitive optical coherence tomography (PSOCT) and near infrared spectroscopy (NIRS) catheter to measure lesions during an ablation procedure. By combining both modalities, we overcome their individual limitations and provide complementary metrics. Using the PSOCT-NIRS catheter to analyze lesions, we show that we can mitigate the imaging depth limitations of PSOCT and inform spectral measurements made by NIRS to provide a more informative view of lesion quality.

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Michael Douglass, Reza Mohammadpour, Gauri Srikumar, Alice Qian, Juan Perez, Jonah Majumder, Christine Hendon, Kenneth R. Laurita, Walter J. Hoyt, Ohad Ziv, and Andrew M. Rollins "A multimodal PSOCT-NIRS catheter for ablation of atrial fibrillation", Proc. SPIE 12834, Multimodal Biomedical Imaging XIX, 1283407 (12 March 2024); https://doi.org/10.1117/12.3006074

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KEYWORDS

Ablation

Near infrared spectroscopy

Atrial fibrillation

Tissues

Heart

Optical coherence tomography

Radiofrequency ablation

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