Classification of healthy and cancerous colon tissues based on absorption coefficient spectra

Valentin Kupriyanov; Maria R. Pinheiro; Sónia D. Carvalho; Isa C. Carneiro; Rui M. Henrique; Valery V. Tuchin; Luis M. Oliveira; Marine Amouroux; Yury Kistenev; Walter Blondel

doi:10.1117/12.3021894

18 June 2024 Classification of healthy and cancerous colon tissues based on absorption coefficient spectra

Valentin Kupriyanov, Maria R. Pinheiro, Sónia D. Carvalho, Isa C. Carneiro, Rui M. Henrique, Valery V. Tuchin, Luis M. Oliveira, Marine Amouroux, Yury Kistenev, Walter Blondel

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Proceedings Volume 13010, Tissue Optics and Photonics III; 130100K (2024) https://doi.org/10.1117/12.3021894
Event: SPIE Photonics Europe, 2024, Strasbourg, France

Abstract

Colorectal cancer is the second most common cancer and the second with the highest associated deaths in the world. Methods used in clinical practice for colon cancer diagnosis are fairly effective but quite unpleasant and not always applicable in situations where the patient has symptoms of colonic obstruction. This problem can be solved by the use of optical methods that can be applied less invasively.

This study presents the results of classification of cancerous and healthy colon tissue absorption coefficient spectra. The absorption coefficient was measured using direct calculations from the total reflectance and total transmittance spectra obtained ex vivo. Classification was performed using support vector machine, multilayer perceptron and linear discriminant analysis.

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Valentin Kupriyanov, Maria R. Pinheiro, Sónia D. Carvalho, Isa C. Carneiro, Rui M. Henrique, Valery V. Tuchin, Luis M. Oliveira, Marine Amouroux, Yury Kistenev, and Walter Blondel "Classification of healthy and cancerous colon tissues based on absorption coefficient spectra", Proc. SPIE 13010, Tissue Optics and Photonics III, 130100K (18 June 2024); https://doi.org/10.1117/12.3021894

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