Near-infrared reflectance spectroscopy as an in-process control tool in the pharmaceutical industry

Chris M. Harland; Brian Davies

doi:10.1117/12.22312

1 October 1990 Near-infrared reflectance spectroscopy as an in-process control tool in the pharmaceutical industry

Chris M. Harland, Brian Davies

Proceedings Volume 1320, Infrared Technology and Applications; (1990) https://doi.org/10.1117/12.22312
Event: Eighth International Conference Infrared Technology and Applications, 1990, London, United Kingdom

Abstract

Near Infrared Reflectance (NIR) spectroscopy has now been in use within Glaxo for over 5 years as a tool to provide rapid analysis. Analyses are sufficiently robust to be performed alongside the manufacturing process by non-technical staff. This paper describes the strategies employed within Claxo to provide both classification information and quantitative or semi-quantitative data relevant to manufacturing processes using a combination of chemometric techniques and NIR spectroscopy's sampling advantages.

Citation Download Citation

Chris M. Harland and Brian Davies "Near-infrared reflectance spectroscopy as an in-process control tool in the pharmaceutical industry", Proc. SPIE 1320, Infrared Technology and Applications, (1 October 1990); https://doi.org/10.1117/12.22312

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