Paper
10 January 2025 Image reconstruction based on graph structure for MRI-guided diffuse optical tomography
Peiwen Zou, Chengpu Wei, Ting Hu, Zhe Li, Zhonghua Sun, Kebin Jia, Jinchao Feng
Author Affiliations +
Proceedings Volume 13507, Seventeenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2024); 135070V (2025) https://doi.org/10.1117/12.3057897
Event: Seventeenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2024), 2024, Shaya, China
Abstract
Diffuse Optical Tomography (DOT) is a non-invasive, label-free imaging technique widely used in applications such as breast cancer diagnosis and brain imaging. It allows for the quantitative measurement of tissue functional parameters, including the concentrations of oxyhemoglobin, deoxyhemoglobin, and water. However, the quality of reconstructed images is poor due to light scattering. To address this challenge, one effective strategy is to incorporate anatomical information from high-resolution imaging to guide DOT reconstruction. In this study, a new approach (GRI) is developed to leverage MRI images based on graph structure for DOT reconstruction. And its feasibility and effectiveness were evaluated with numerical simulations. The results indicate that GRI significantly improves the Structural Similarity Index (SSIM) of reconstructed total hemoglobin (HbT) images, outperforming conventional Tikhonov regularization and Direct Regularization Imaging (DRI) method by more than 63% and 82%, respectively. These findings are further supported by experiments using real patient data, which demonstrate GRI’s potential in breast cancer diagnosis.
(2025) Published by SPIE. Downloading of the abstract is permitted for personal use only.
Peiwen Zou, Chengpu Wei, Ting Hu, Zhe Li, Zhonghua Sun, Kebin Jia, and Jinchao Feng "Image reconstruction based on graph structure for MRI-guided diffuse optical tomography", Proc. SPIE 13507, Seventeenth International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2024), 135070V (10 January 2025); https://doi.org/10.1117/12.3057897
Advertisement
Advertisement
RIGHTS & PERMISSIONS
Get copyright permission  Get copyright permission on Copyright Marketplace
KEYWORDS
Image restoration

Magnetic resonance imaging

Medical image reconstruction

Reconstruction algorithms

Image quality

Chromophores

Diffuse optical tomography

Back to Top