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1 March 1991 Planar waveguide optical immunosensors
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Proceedings Volume 1368, Chemical, Biochemical, and Environmental Fiber Sensors II; (1991)
Event: SPIE Microelectronic Interconnect and Integrated Processing Symposium, 1990, San Jose, United States
Monoclonal antibodies were covalently bonded to the surfaces of planar waveguides to confer immunoreacth''ity. Silver-ion diffused waveguides were used to measure theophylline concentrations in a fluorescence immunoassay and silicon nitride waveguides were used to detect theophylline in an absorbance-based immunoassay. Liposomes were employed in both assays as the optically detectable label in a competitive reaction to monitor antigen-antibody complexation. Regeneration of the active antibody site will be discussed.
© (1991) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Steven J. Choquette, Laurie E. Locascio-Brown, and Richard A. Durst "Planar waveguide optical immunosensors", Proc. SPIE 1368, Chemical, Biochemical, and Environmental Fiber Sensors II, (1 March 1991);

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