Time-resolved polarization luminescence spectroscopy of hematoporphyrin in liposomes

Elena B. Chernyaeva; N. A. Golubeva; Nikolai I. Koroteev; Oleg I. Lobanov; A. G. Vardanyan

doi:10.1117/12.47503

1 April 1991 Time-resolved polarization luminescence spectroscopy of hematoporphyrin in liposomes

Elena B. Chernyaeva, N. A. Golubeva, Nikolai I. Koroteev, Oleg I. Lobanov, A. G. Vardanyan

Proceedings Volume 1402, USSR-CSFR Joint Seminar on Nonlinear Optics in Control, Diagnostics, and Modeling of Biophysical Processes; (1991) https://doi.org/10.1117/12.47503
Event: USSR-CSFR Joint Seminar on Nonlinear Optics in Control, Diagnostics and Modeling, 1990, Koshice-Prague, Czechoslovakia

Abstract

Results of time-resolved fluorescence anisotropy decay kinetics measurements of hematoporphyrin (Hp) in liposomes are presented. The increase of average rotational correlation time with the increase of incubation time is an evidence of HP aggregation in lipid bilayer. Experiments were carried out with suspensions of monolayer liposomes from natural phosphatidyicholine (PC). The time-resolved polarized fluorescence spectroscopy with time-correlated single photon counting technique was used. The possibility of different types of aggregates formation in lipid bilayer is discussed.

Citation Download Citation

Elena B. Chernyaeva, N. A. Golubeva, Nikolai I. Koroteev, Oleg I. Lobanov, and A. G. Vardanyan "Time-resolved polarization luminescence spectroscopy of hematoporphyrin in liposomes", Proc. SPIE 1402, USSR-CSFR Joint Seminar on Nonlinear Optics in Control, Diagnostics, and Modeling of Biophysical Processes, (1 April 1991); https://doi.org/10.1117/12.47503

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