1 July 1991 Detection of general anesthetics using a fluorescence-based sensor: incorporation of a single-fiber approach
Author Affiliations +
Proceedings Volume 1420, Optical Fibers in Medicine VI; (1991) https://doi.org/10.1117/12.43860
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States
A fiber-optic sensor for general anesthetics based on the phase transition of phospholipid vesicles has been developed and reported previously. The instrumentation and optics have been designed using two fibers and constructed in a portable configuration to allow multi-site testing. Because the phase transition is highly dependent on the surrounding temperature, it is necessary to obtain a temperature reference signal; use of a single-fiber configuration for both sample and reference permits the addition of a temperature transducer in the optrode without increasing its size. Because of the extreme turbidity of the liposomes, current theory does not predict whether a two-fiber or one-fiber approach will provide superior signal strength. The signal efficiency of the original dual-fiber configuration has been compared to that of a second dual-fiber configuration and a single-fiber system incorporating a fiber-optic coupler. Despite the reduced excitation power reaching the optrode, the single-fiber configuration produces a superior signal intensity. The addition of a custom-made Y-shaped fiber coupler enables switching from a dual-fiber design to the single-fiber optrode design without sacrificing portability.
© (1991) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Susan B. Abrams, Hillary L. MacDonald, Paul Yager, "Detection of general anesthetics using a fluorescence-based sensor: incorporation of a single-fiber approach", Proc. SPIE 1420, Optical Fibers in Medicine VI, (1 July 1991); doi: 10.1117/12.43860; https://doi.org/10.1117/12.43860


Optical fiber gas sensor stability research
Proceedings of SPIE (August 13 1998)
Sensitivity Analysis Of Evanescent Fiber Optic Sensors
Proceedings of SPIE (June 15 1989)
Performance predictions of a fiber-optic temperature sensor
Proceedings of SPIE (December 18 2002)
Sensitive fiber-optic immunoassay
Proceedings of SPIE (July 01 1991)

Back to Top