1 July 1991 Preliminary results with sutured colonic anastomoses reinforced with dye-enhanced fibrinogen and a diode laser
Author Affiliations +
Proceedings Volume 1421, Lasers in Urology, Laparoscopy, and General Surgery; (1991) https://doi.org/10.1117/12.43926
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States
Abstract
A common cause of morbidity in patients recovering from bowel surgery is leakage from colonic anastomoses. A technique utilizing a laser activated protein solder to strengthen colonic anastomoses in a canine model was evaluated. Following creation of six single-layer interrupted suture anastomoses in four dogs, a protein solder consisting of indocyanine green dye and fibrinogen was topically appied to the serosal surface and exposed to 808 nm continuous wave diode laser energy. Immediately following anastomosis, the mean leakage pressure of sutures alone was 129 +/- 14 mm hg (n equals 6), while the mean leakage pressure of sutures reinforced with the laser welded solder was 312 +/- 32 mm hg (n equals 6) (p <0.001). Histologic examination of sections take through the anastomosis demonstrated a layer of fibrinogen across the anastomotic gap without evidence of thermal injury. Laser activated protein solder significantly enhances the immediate strength of sutured colonic anastomoses without causing appreciable thermal injury to surrounding tissues.
© (1991) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Steven K. Libutti, Matthew R. Williams, Mehmet Cengiz Oz, Kenneth A. Forde, Lawrence S. Bass, Samuel Weinstein, Joseph S. Auteri, Michael R. Treat, and Roman Nowygrod "Preliminary results with sutured colonic anastomoses reinforced with dye-enhanced fibrinogen and a diode laser", Proc. SPIE 1421, Lasers in Urology, Laparoscopy, and General Surgery, (1 July 1991); doi: 10.1117/12.43926; https://doi.org/10.1117/12.43926
PROCEEDINGS
4 PAGES


SHARE
Advertisement
Advertisement
Back to Top