Electron microscopic study on black pig skin irradiated with pulsed dye laser (504 nm)

Yukio Yasuda M.D.; Oon Tian Tan M.D.; Amal K. Kurban M.D.; Sadao Tsukada M.D.

doi:10.1117/12.43940

1 June 1991 Electron microscopic study on black pig skin irradiated with pulsed dye laser (504 nm)

Yukio Yasuda M.D., Oon Tian Tan M.D., Amal K. Kurban M.D., Sadao Tsukada M.D.

Proceedings Volume 1422, Lasers in Dermatology and Tissue Welding; (1991) https://doi.org/10.1117/12.43940
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

Selective damage of epidermal pigment cells induced by 504 nm pulsed dye laser at different pulse durations and fluence on black pig skin was examined electron microscopically. Epidermal melanosomes were satisfactorily disrupted at shorter pulse duration (100 ns). Epidermal blister formation and necrosis were seen at 2 days postirradiation, and reepithelization was evident at 7 days postirradiation in all specimens. Repigmentation was evident 21 to 56 days after irradiation. Histological pigmentary incontinence was evident at 2 days and persisted until 56 days postirradiation. This phenomenon was observed more frequently in skin exposed to longer pulse duration and at low fluences. Optimal parameters required to induce epidermal melanosome disruption using the 504 nm pulsed dye laser will be discussed.

Citation Download Citation

Yukio Yasuda M.D., Oon Tian Tan M.D., Amal K. Kurban M.D., and Sadao Tsukada M.D. "Electron microscopic study on black pig skin irradiated with pulsed dye laser (504 nm)", Proc. SPIE 1422, Lasers in Dermatology and Tissue Welding, (1 June 1991); https://doi.org/10.1117/12.43940

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