Hyperthermia treatment of spontaneously occurring oral cavity tumors using a computer-controlled Nd:YAG laser system

Masoud Panjehpour; Bergein F. Overholt M.D.; Donita L. Frazier D.V.M.; Edward R. Klebanow D.V.M.

doi:10.1117/12.44005

1 May 1991 Hyperthermia treatment of spontaneously occurring oral cavity tumors using a computer-controlled Nd:YAG laser system

Masoud Panjehpour, Bergein F. Overholt M.D., Donita L. Frazier D.V.M., Edward R. Klebanow D.V.M.

Author Affiliations +

Proceedings Volume 1424, Lasers in Orthopedic, Dental, and Veterinary Medicine; (1991) https://doi.org/10.1117/12.44005
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

Conventional hyperthermia treatment of superficial tumors in the oral cavity is difficult due to inability in accessing the lesion. A new hyperthermia technique employing near infrared Nd:YAG irradiation delivered through an optical fiber is introduced for heating oral and nasal tumors in animals. This system consisted of an Nd:YAG laser, a He-Ne laser, a computer controlled optical shutter, an interstitial thermometer, computer and a printer. The tumors were heated via surface illumination of the lesion. A thermocouple implanted in the base of the tumor provided temperature feedback for laser energy regulation. Three spontaneously occurring canine (two squamous cell carcinoma on the gum, one pigmented melanoma on the hard palate) and one feline tumor (squamous cell carcinoma on the nose) have been treated with the Nd:YAG laser-induced hyperthermia delivered following radiation therapy. The tumor temperature was maintained between 43.2-43.5 degree(s)C for one hour. Nd:YAG hyperthermia allowed efficient delivery of heat to veterinary oral and nasal lesions otherwise impossible to treat with conventional heating techniques.

Citation Download Citation

Masoud Panjehpour, Bergein F. Overholt M.D., Donita L. Frazier D.V.M., and Edward R. Klebanow D.V.M. "Hyperthermia treatment of spontaneously occurring oral cavity tumors using a computer-controlled Nd:YAG laser system", Proc. SPIE 1424, Lasers in Orthopedic, Dental, and Veterinary Medicine, (1 May 1991); https://doi.org/10.1117/12.44005

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