Evaluation of Nile Blue E chalcogen analogs as PDT agents

James W. Foley; Louis Cincotta; Anthony H. Cincotta

doi:10.1117/12.44060

1 June 1991 Evaluation of Nile Blue E chalcogen analogs as PDT agents

James W. Foley, Louis Cincotta, Anthony H. Cincotta

Proceedings Volume 1426, Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques; (1991) https://doi.org/10.1117/12.44060
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

The photodynamic therapeutic properties of the oxygen containing benzophenoxazine dye Nile Blue E, NBEO, and its sulfur and selenium analogs, NBES and NBESe, were evaluated in cell culture using a murine mammary sarcoma (EMT-6) cell line. The photosensitizing efficacies of the dyes were found to correlate with their ability to generate singlet oxygen and to increase in the order: NBEO

Citation Download Citation

James W. Foley, Louis Cincotta, and Anthony H. Cincotta "Evaluation of Nile Blue E chalcogen analogs as PDT agents", Proc. SPIE 1426, Optical Methods for Tumor Treatment and Early Diagnosis: Mechanisms and Techniques, (1 June 1991); https://doi.org/10.1117/12.44060

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