Many issues must be addressed and resolved in order to bring a complete imaging workstation into everyday use by radiologists and medical researchers. Important design issues for developing an imaging workstation include image quality, system response time, the user interface and image storage. The Image Computing Systems Laboratory (ICSL) at the University of Washington has been developing a series of inexpensive graphics and image processing workstations with high performance by taking advantage of a sharp decrease in hardware costs, increasingly more powerful VLSI chips, and versatile personal computers and workstations. After gaining experience with two previous image processing systems, UWGSP3 (University of Washington Graphics System Processor #3), a third-generation workstation based on the NeXT Computer and UWGSP3-HI, a host-independent version, that can work with any host computer via an interface card, were developed. UWGSP3, a highly integrated, low-cost workstation, is a complete image display and computing system capable of meeting many of the requirements of a medical imaging workstation provided that a suitable user interface is developed. To demonstrate this capability, RadGSP, a prototype user interface and application software for radiologist use, has been developed. This paper will first describe the UWGSP3-HI system for background information before describing the implementation and evaluation of RadGSP, and current radiology imaging workstation research in progress at ICSL.