Langmuir-Blodgett films of immunoglobulin G and direct immunochemical sensing

Illarion V. Turko; Irene A. Pikuleva; Igor S. Yurkevich; Vadim L. Chashchin

doi:10.1117/12.47123

1 September 1991 Langmuir-Blodgett films of immunoglobulin G and direct immunochemical sensing

Illarion V. Turko, Irene A. Pikuleva, Igor S. Yurkevich, Vadim L. Chashchin

Author Affiliations +

Proceedings Volume 1510, Chemical and Medical Sensors; (1991) https://doi.org/10.1117/12.47123
Event: ECO4 (The Hague '91), 1991, The Hague, Netherlands

Abstract

Langmuir-Blodgett technique is shown to be a suitable method for construction of the functionally-oriented layers of immunoglobulin G (IgG) which bind antigen better than in the case of chemical immobilization of IgG on the same substrate. It is assumed that the fluorescent detection of the conformational changes in the molecule of IgG or in the regular structures of IgG molecules after the interaction with antigen can be used for the development of the new type of immunosensors.

Citation Download Citation

Illarion V. Turko, Irene A. Pikuleva, Igor S. Yurkevich, and Vadim L. Chashchin "Langmuir-Blodgett films of immunoglobulin G and direct immunochemical sensing", Proc. SPIE 1510, Chemical and Medical Sensors, (1 September 1991); https://doi.org/10.1117/12.47123

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