In-vivo blood flow velocity measurements using the self-mixing effect in a fiber-coupled semiconductor laser

Marco H. Koelink; M. Slot; Frits F. M. de Mul; Jan Greve; Reindert Graaff; A. C. M. Dassel; Jan G. Aarnoudse

doi:10.1117/12.45984

1 August 1991 In-vivo blood flow velocity measurements using the self-mixing effect in a fiber-coupled semiconductor laser

Marco H. Koelink, M. Slot, Frits F. M. de Mul, Jan Greve, Reindert Graaff, A. C. M. Dassel, Jan G. Aarnoudse

Author Affiliations +

Proceedings Volume 1511, Fiber Optic Sensors: Engineering and Applications; (1991) https://doi.org/10.1117/12.45984
Event: ECO4 (The Hague '91), 1991, The Hague, Netherlands

Abstract

A laser Doppler velocimeter has been developed to measure blood flow velocity in vivo. It consists of a semiconductor laser coupled to a fiber. Laser light is guided into a blood vessel and backscattered light (by red blood cells) is guided back into the laser. The backscattered Doppler shifted light produces an intensity modulation of the laser (self-mixing effect). The beat-frequency of the intensity modulation is related to the Doppler shift of the backscattered light. A model is presented to calculate modulation signals, and results of measurements in vitro and in vivo are shown.

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Marco H. Koelink, M. Slot, Frits F. M. de Mul, Jan Greve, Reindert Graaff, A. C. M. Dassel, and Jan G. Aarnoudse "In-vivo blood flow velocity measurements using the self-mixing effect in a fiber-coupled semiconductor laser", Proc. SPIE 1511, Fiber Optic Sensors: Engineering and Applications, (1 August 1991); https://doi.org/10.1117/12.45984

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