1 November 1991 Tumor detection using time-resolved light transillumination
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A time-gated technique to reduce the effect of light scattering when transilluminating turbid media such as tissue is demonstrated. The concept is based on transillumination with picosecond laser pulses and time-resolved detection. By detecting only the photons with the shortest travelling time, and thus the least scattered photons, the contrast can be enhanced. Measurements on a tissue phantom as well as breast tissue in vitro are presented. It is demonstrated that the spatial resolution can be enhanced by using the time-gated technique. It is also shown that differences in scattering properties may be more pronounced than differences in absorption properties when demarcating tumor from normal tissue.
© (1991) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Roger Berg, Roger Berg, Stefan Andersson-Engels, Stefan Andersson-Engels, Olof Jarlman, Olof Jarlman, Sune Svanberg, Sune Svanberg, } "Tumor detection using time-resolved light transillumination", Proc. SPIE 1525, Future Trends in Biomedical Applications of Lasers, (1 November 1991); doi: 10.1117/12.48209; https://doi.org/10.1117/12.48209


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