1 March 1992 Spray-jet assembly interface for the coupling of reversed-phase narrow-bore LC and FTIR spectrometry
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Proceedings Volume 1575, 8th Intl Conf on Fourier Transform Spectroscopy; (1992) https://doi.org/10.1117/12.56475
Event: Eighth International Conference on Fourier Transform Spectroscopy, 1991, Lubeck-Travemunde, Germany
Abstract
Reversed phase liquid chromatography (RPLC) has been coupled to Fourier transform infrared spectrometry (FTIR) via solvent elimination and effluent deposition using a spray jet assembly. The chromatographic separation is hardly affected. Identification limits are in the 10 - 20 ng range. The system can handle eluent containing up to 40% water. The usefulness of the interface in impurity profiling of steroids is demonstrated.
© (1992) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
G. W. Somsen, Cees Gooijer, Udo A. T. Brinkman, Nel H. Velthorst, Tom Visser, A. P. J. M. de Jong, "Spray-jet assembly interface for the coupling of reversed-phase narrow-bore LC and FTIR spectrometry", Proc. SPIE 1575, 8th Intl Conf on Fourier Transform Spectroscopy, (1 March 1992); doi: 10.1117/12.56475; https://doi.org/10.1117/12.56475
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