5 March 1993 Experimental study of the effects of helium-neon laser radiation on repair of injured tendon
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Proceedings Volume 1616, International Conference on Photodynamic Therapy and Laser Medicine; (1993) https://doi.org/10.1117/12.136959
Event: International Conference on Photodynamic Therapy and Laser Medicine, 1991, Beijing, China
Abstract
Despite extensive research into the biology of tendon healing, predictably restoring normal function to a digit after a flexor tendon laceration remains one of the most difficult problems facing the hand surgeon. The challenge of simultaneously achieving tendon healing while minimizing the peritendinous scar formation, which limits tendon gliding, has captured the attention of investigators for many years. It has been said that low-power density helium-neon laser radiation had effects on anti-inflammation, detumescence, progressive wound healing, and reducing intestinal adhesions. This experimental study aims at whether helium-neon laser can reduce injured tendon adhesions and improve functional recovery of the injured tendon. Fifty white Leghorn hens were used. Ten were randomly assigned as a normal control group, the other forty were used in the operation. After anesthetizing them with Amytal, a half of the profundus tendons of the second and third foretoes on both sides of the feet were cut. Postoperatively, the hens moved freely in the cages. One side of the toes operated on were randomly chosen as a treatment group, the other side served as an untreated control group. The injured tendon toes in the treatment group were irradiated for twenty minutes daily with a fiber light needle of helium-neon laser therapeutic apparatus (wavelength, 6328 angstroms) at a constant power density of 12.74 mW/cm2, the first exposure taking place 24 hours after the operation. The longest course of treatment was 3 weeks. The control group was not irradiated. At 3 days, 1, 2, 3, and 5 weeks after surgery, 8 hens were sacrificed and their tendons were examined. The experimental results: (1) active, passive flexion and tendon gliding functional recovery were significantly better in the treatment group (p < 0.01); (2) width and thickness of the tendon at the cut site were significantly smaller in the treatment group (p < 0.01); (3) degrees of tendon adhesions were significantly lighter in the treatment group (p < 0.05). The experimental results demonstrate helium-neon laser radiation had significant effects on anti-inflammation, detumescence, progressive hematoma absorbing, inhibiting the tendon extrinsic healing, reducing tendon adhesions, improving the tendon intrinsic healing, i.e., stimulating epitenon and endotenon cells proliferation and migrating into the gap, stimulating collagen synthesis in the tendon gap, and enhancing the late remodeling of fibrous peritendonous adhesion.
© (1993) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Yong-Qing Xu, Yong-Qing Xu, Zhu-Yi Li, Zhu-Yi Li, Long-Jiang Weng, Long-Jiang Weng, Mei An, Mei An, Kai-Yun Li, Kai-Yun Li, Shao-Rong Chen, Shao-Rong Chen, Jian-Xin Wang, Jian-Xin Wang, Yu Lu, Yu Lu, "Experimental study of the effects of helium-neon laser radiation on repair of injured tendon", Proc. SPIE 1616, International Conference on Photodynamic Therapy and Laser Medicine, (5 March 1993); doi: 10.1117/12.136959; https://doi.org/10.1117/12.136959
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