5 March 1993 Photodynamic effects of Can-Sha photosensitizer on transplanted tumors in mice
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Proceedings Volume 1616, International Conference on Photodynamic Therapy and Laser Medicine; (1993) https://doi.org/10.1117/12.137023
Event: International Conference on Photodynamic Therapy and Laser Medicine, 1991, Beijing, China
Abstract
Can-sha photosensitizer (CPS) extracted from the silkworm excreta (a Chinese herb) was administered to tumor bearing mice by iv or the intragastrointestinal route in dosages of 50 mg/kg and 550 mg/kg, respectively. Six to ten hours later the tumorous site was irradiated with light. The results showed that the tumor inhibition rates were 69 - 98% by iv and 62 - 79% by intraduodenal (id) injection, but no photodynamic effect was found in the tumors of mice after administering CPD by p.o. 3H-TdR or 3-uR incorporation ability of the tumor cells pretreated with the drug and light was significantly inhibited.
© (1993) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Jixiu Zhong, Jixiu Zhong, Lingling Zhu, Lingling Zhu, Weijia Li, Weijia Li, Yonghua Yang, Yonghua Yang, } "Photodynamic effects of Can-Sha photosensitizer on transplanted tumors in mice", Proc. SPIE 1616, International Conference on Photodynamic Therapy and Laser Medicine, (5 March 1993); doi: 10.1117/12.137023; https://doi.org/10.1117/12.137023
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