5 March 1993 Three-year experience in the application of PDT in the treatment of lung cancer
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Proceedings Volume 1616, International Conference on Photodynamic Therapy and Laser Medicine; (1993) https://doi.org/10.1117/12.136956
Event: International Conference on Photodynamic Therapy and Laser Medicine, 1991, Beijing, China
Abstract
During a 3 year period, 20 patients with morphologically proven squamous cell carcinoma of the trachea or bronchi have been treated by photoradiation therapy (PRT). A Bulgarian gold vapor laser and hematoporphyrin of `Jacopo Monico,' Italy were used. The photosensitizer was applied intravenously 24 - 48 h prior to PDT. The median realized energy dose was 410 J/cm2 for each patient with a middle power of 180 mW. In 5 of all the cases we performed two sessions. The obtained therapeutic results are as follows: CR -- one case (5%), SR -- 10 cases (50%), NR -- 3 cases (15%). The median survival of the patients with advanced cancer was 13.3 months. At the end of 1990 three patients were alive. Our experience shows that PRT is a promising palliative method in cases of advanced carcinoma for the recanalization of airways.
© (1993) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
D. Kostadinov, Emil Benov, K. Mitchev, V. Vlasov, Giulio Jori, "Three-year experience in the application of PDT in the treatment of lung cancer", Proc. SPIE 1616, International Conference on Photodynamic Therapy and Laser Medicine, (5 March 1993); doi: 10.1117/12.136956; https://doi.org/10.1117/12.136956
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