1 May 1992 Scanning force microscopy of circular DNA and chromatin in air and propanol
Author Affiliations +
Proceedings Volume 1639, Scanning Probe Microscopies; (1992) https://doi.org/10.1117/12.58189
Event: OE/LASE '92, 1992, Los Angeles, CA, United States
High resolution electron micrographs of microtips show nanometer surface irregularities. We propose that the lower contact forces, and consequent greater sensitivity, from imaging in propanol enables small biomolecules to be imaged at higher resolution by these 'nanotips'. However, larger molecules, such as the nucleosomes of chromatin, are still imaged by the bulk of the tip and no improvement of resolution is obtained.
© (1992) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
James Vesenka, James Vesenka, Helen G. Hansma, Helen G. Hansma, Cristina Siegerist, Cristina Siegerist, Giuliano Siligardi, Giuliano Siligardi, Eric Schabtach, Eric Schabtach, Carlos J. Bustamante, Carlos J. Bustamante, "Scanning force microscopy of circular DNA and chromatin in air and propanol", Proc. SPIE 1639, Scanning Probe Microscopies, (1 May 1992); doi: 10.1117/12.58189; https://doi.org/10.1117/12.58189

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