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28 August 1992 Comparison of holmium:YSGG versus Nd:YAG in an artificial circulation model
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Abstract
The effects of pulsed Holmium:Yttrium Scandium Gallium Garnet (Ho:YSGG) laser energy on cadaveric human arterial tissue were compared with our current clinical laser energy source -- Neodymium:Yttrium Aluminum Garnet (Nd:YAG). Dose response, arterial recanalization in an artificial circulation model, and debris formation were assessed. Ho:YSGG was found to be more efficient at ablation than the Nd:YAG, and created a similar quantity of debris during recanalization. Ho:YSGG was also able to ablate calcified arterial occlusions which the Nd:YAG could not. However, Ho:YSGG led to more arterial perforations during the attempted recanalization of very curved vessels, most likely due to the combination of a heavily absorbed wavelength and the relative inflexibility of the 600 micrometers optical fiber used in the experiments. In spite of this shortcoming, Ho:YSGG remains an attractive source for laser angioplasty.
© (1992) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Roy N. Lawrence, Jonathan A. Michaels M.D., and Stephen G. Bown "Comparison of holmium:YSGG versus Nd:YAG in an artificial circulation model", Proc. SPIE 1642, Diagnostic and Therapeutic Cardiovascular Interventions II, (28 August 1992); https://doi.org/10.1117/12.137294
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