28 August 1992 Comparison of holmium:YSGG versus Nd:YAG in an artificial circulation model
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The effects of pulsed Holmium:Yttrium Scandium Gallium Garnet (Ho:YSGG) laser energy on cadaveric human arterial tissue were compared with our current clinical laser energy source -- Neodymium:Yttrium Aluminum Garnet (Nd:YAG). Dose response, arterial recanalization in an artificial circulation model, and debris formation were assessed. Ho:YSGG was found to be more efficient at ablation than the Nd:YAG, and created a similar quantity of debris during recanalization. Ho:YSGG was also able to ablate calcified arterial occlusions which the Nd:YAG could not. However, Ho:YSGG led to more arterial perforations during the attempted recanalization of very curved vessels, most likely due to the combination of a heavily absorbed wavelength and the relative inflexibility of the 600 micrometers optical fiber used in the experiments. In spite of this shortcoming, Ho:YSGG remains an attractive source for laser angioplasty.
© (1992) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Roy N. Lawrence, Roy N. Lawrence, Jonathan A. Michaels, Jonathan A. Michaels, Stephen G. Bown, Stephen G. Bown, } "Comparison of holmium:YSGG versus Nd:YAG in an artificial circulation model", Proc. SPIE 1642, Diagnostic and Therapeutic Cardiovascular Interventions II, (28 August 1992); doi: 10.1117/12.137294; https://doi.org/10.1117/12.137294


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