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28 August 1992 Lesion-specific laser catheters for angioplasty
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Since no one laser catheter can treat all types of disease, a new family of `lesion-specific' devices was evaluated with a holmium laser source. Three-hundred-thirty-one patients (avg. 60 years) with symptomatic coronary disease were studied. Average lesion length was 1.2 cm. A 1.4, 1.5, 1.7, or 2.0 mm, tapered-tip or non-tapered, multifiber catheter (Eclipse, Palo Alto, Calif.) was advanced over the wire while emitting 250 - 600 mj/pulse at 5 Hz. Mean percent stenosis decreased from 89% to 57% after lasing with a mean of 140 pulses. Complications were infrequent. Overall procedural success was 95%. The conclusion is that specialized laser catheters delivering holmium laser energy are capable of reducing the severity of coronary stenoses including balloon angioplasty failures and bypass graft failures. Follow up studies are in progress to assess long term efficacy.
© (1992) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Douglas Murphy-Chutorian "Lesion-specific laser catheters for angioplasty", Proc. SPIE 1642, Diagnostic and Therapeutic Cardiovascular Interventions II, (28 August 1992);

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