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28 August 1992 Multifiber coronary laser angioplasty with a holmium:YAG laser
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Percutaneous coronary laser angioplasty with a multifiber catheter coupled to a pulsed holmium:YAG (2.1 micrometers ) laser was performed on seven lesions in six patients who were candidates for elective coronary angioplasty. Following passage of a guidewire across the lesion the laser catheter was advanced to the lesion. The laser was used in the free running mode with 250 microsecond(s) ec pulses and delivering 50 mJ to 400 mJ per pulse at 5 Hz. Two sizes of laser catheters were used 1.6 mm and 2.0 mm in diameter. The 1.6 mm diameter catheter delivered fluences ranging from 335 mJ/mm2 to 2,680 mJ/mm2 and the 2.0 mm multifiber catheter delivered fluences of 219 mJ/mm2 to 1,754 mJ/mm2. Successful recanalization was obtained in every case. The average stenosis reduction following laser angioplasty alone was from a baseline of 96.6 +/- 3.5% to 38.6 +/- 24.1% (p < 0.01). Six of the seven lesions required adjunctive therapy with other angioplasty devices for further reduction of the stenosis to 12.9 +/- 4.9%. There were no complications specifically related to the laser angioplasty procedure. Two patients, however, did have abrupt occlusion of the treated artery following adjunctive angioplasty treatment. In this small series of patients we are encouraged by the ability of this laser angioplasty system to successfully recanalize coronary artery stenoses in a safe and effective manner. Larger numbers of patients are required to confirm these results and further investigate the clinical utility of this device.
© (1992) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Christopher J. White M.D., Stephen R. Ramee M.D., Tyrone J. Collins M.D., Juan E. Mesa M.D., and Ashit Jain M.D. "Multifiber coronary laser angioplasty with a holmium:YAG laser", Proc. SPIE 1642, Diagnostic and Therapeutic Cardiovascular Interventions II, (28 August 1992);

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