28 August 1992 Tissue ablation with excimer laser and multiple-fiber catheters: effects of optical fiber density and fluence
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Proceedings Volume 1642, Diagnostic and Therapeutic Cardiovascular Interventions II; (1992); doi: 10.1117/12.137297
Event: OE/LASE '92, 1992, Los Angeles, CA, United States
Abstract
This study was performed to assess the ablational properties of the 1.4, 1.7, and 2.0 wire- guided multiple fiber catheters coupled to an XeCl excimer laser. The samples of human post- mortem aorta were irradiated in blood at fluences of 40, 50, and 60 mJ/mm2. Our results indicate: (1) An increase in the active irradiation coverage results and an increase in the ablation efficiency. (2) The ablation efficiency is not fluence-related using the 1.4 or 1.7 multiple fiber catheter but depends on fluence using the 2.0 multiple fiber catheter. (3) The depth of tissue ablated with the multiple fiber catheter depends primarily upon the proportion of the active irradiation coverage at the catheter tip. (4) The 2.0 multiple fiber catheter induces craters surrounded by a larger zone of tissue damage than that observed with the 1.4 or 1.7 multiple fiber catheter. (5) The 2.0 multiple fiber catheter should be used cautiously in laser angioplasty because of its high penetration and its possibility of arterial wall damage.
© (1992) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Jan Kvasnicka, Fumitaka Nakamura, Herbert J. Geschwind, Francoise Lange, "Tissue ablation with excimer laser and multiple-fiber catheters: effects of optical fiber density and fluence", Proc. SPIE 1642, Diagnostic and Therapeutic Cardiovascular Interventions II, (28 August 1992); doi: 10.1117/12.137297; https://doi.org/10.1117/12.137297
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KEYWORDS
Tissues

Laser ablation

Excimer lasers

Laser tissue interaction

Optical fibers

Fiber lasers

Blood

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