1 June 1992 Effects of additives on laser-assisted fibrinogen bonding
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Abstract
In order to produce a solder for Laser-Assisted Tissue Bonding (LATB) with better tactile characteristics and shelf life, plasma-derived fibrinogen concentrate has been augmented with various additives, including anionic polysaccharides, anti-fibrinolytic agents, and preservatives. For comparison of this new, compounded 'solder' with the pure, plasma- derived fibrinogen concentrate an in vivo tissue 'weld' assay was devised. While further analyses must be done to assess more critical healing time periods and characteristics, this study is an affirmation that the plasma-derived, protein concentrates, with or without certain additives, offer effective alternatives to suture repair.
© (1992) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
G. Michael Lemole, G. Michael Lemole, Robert C. Ashton, Robert C. Ashton, Mehmet Cengiz Oz, Mehmet Cengiz Oz, I. Arikan, I. Arikan, D. Arikan, D. Arikan, Gerald M. Lemole, Gerald M. Lemole, } "Effects of additives on laser-assisted fibrinogen bonding", Proc. SPIE 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III, (1 June 1992); doi: 10.1117/12.137352; https://doi.org/10.1117/12.137352
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