1 June 1992 Histopathologic changes occurring in the prostate following transurethral laser prostatectomy
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Serial changes occurring in the canine prostate were studied at 1 and 3 hours; 1, 2, 4, and 7 days; and 2, 3, 5, 7, and 20 weeks following transurethral laser prostatectomy using the Neodymium:YAG (Nd:YAG) laser which delivered 60 watts (W) of power for 60 seconds at 4 positions (2, 5,8, and 11 o'clock) through a Lateralase' 2.5-mmfiber. A well-demarcated sphere of thermal necrosis measuring 2.7 cm in diameter was present immediately which, within 24 hours, had begun liquefaction and was showing multiple areas of cavitation. At 1 week, the area of cavitation had coalesced to form a central cavity and within 5weeks, the ectatic cavity had been lined by transitional epithelium. These observations confirm our previous surgical and clinical impression of being able to satisfactorily perform an effective transurethral laser prostatectomy with reproducible and consistent results without using sophisticated monitoring devices.
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Douglas E. Johnson, Douglas E. Johnson, Roger E. Price, Roger E. Price, Douglas M. Cromeens, Douglas M. Cromeens, "Histopathologic changes occurring in the prostate following transurethral laser prostatectomy", Proc. SPIE 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III, (1 June 1992); doi: 10.1117/12.137346; https://doi.org/10.1117/12.137346

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