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1 June 1992 MR-guided laser interventions
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Low-power interstitial thermal therapy using a 1064 nm Nd:YAG laser and a newly designed fiberoptic transmission system, the ITT laser fiber, is a promising therapeutic approach in the treatment of cerebral tumors. After CT-guided stereotactic implantation of an applicator probe, we performed laser-induced interstitial thermal therapy in a patient with an astrocytomas WHO grade II under simultaneous magnetic resonance imaging (MRI) control. In order to assess the effects of the treatment a 2D-Flash sequence with an acquisition time of 15 sec was used. It could be demonstrated that laser-tissue interactions progressed with duration of irradiation depending on laser powers applied. There was a well-defined area of tissue necrosis with a maximum size of 17 mm in diameter in the center of the tumor and a small zone of transient perifocal edema. With regard to experimental studies, it seems to be possible to define between reversible and irreversible laser-tissue effects.
© (1992) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Martin Bettag, Frank Ulrich, Wolfgang J. Bock, Thomas Kahn M.D., Hans-Joachim Schwarzmaier M.D., and Stefan Frank F. Hessel "MR-guided laser interventions", Proc. SPIE 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III, (1 June 1992);

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