Near-IR Fourier transform Raman spectroscopy in surgery and medicine: detection of renal stones and bladder cancer

Shuming Nie; Douglas C. B. Redd M.D.; Yunzhi Li; Nai-Teng Yu

doi:10.1117/12.137325

1 June 1992 Near-IR Fourier transform Raman spectroscopy in surgery and medicine: detection of renal stones and bladder cancer

Shuming Nie, Douglas C. B. Redd M.D., Yunzhi Li, Nai-Teng Yu

Author Affiliations +

Proceedings Volume 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III; (1992) https://doi.org/10.1117/12.137325
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

Tissue diagnosis and characterization are critically important to the development and applications of laser-based therapeutic procedures in urology (viz., laser lithotripsy and bladder cancer treatment). Recently, we demonstrated for the first time that the new technique of near-infrared laser excited Fourier transform (FT)-Raman spectroscopy can readily differentiate various types of renal stones and bladder cancer from normal kidney/bladder tissues. It has thus become possible to develop an FT-Raman-based fiberoptic sensor for clinical use in laser lithotripsy and bladder cancer treatment. The future development of such a diagnostic modality will allow a surgeon/physician to take real-time Raman spectra of urinary calculi or cancerous tissue via a flexible fiberoptic probe.

Citation Download Citation

Shuming Nie, Douglas C. B. Redd M.D., Yunzhi Li, and Nai-Teng Yu "Near-IR Fourier transform Raman spectroscopy in surgery and medicine: detection of renal stones and bladder cancer", Proc. SPIE 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III, (1 June 1992); https://doi.org/10.1117/12.137325

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