1 June 1992 Spectroscopy, photokinetics, and cellular effect of far-red and near-infrared absorbing photosensitizers
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Abstract
Two types of photosensitizers are compared here for their singlet oxygen production and in vivo sensitizing capacity: Mg2+ and Zn2+-tetrabenzoporphyrin, which have a strong Q band at the HeNe laser line; and Cd-texaphyrin, with absorption at 770 nm. The singlet oxygen quantum yields in homogeneous solutions were determined by employing a singlet oxygen-destroyable fluorescent target. Photosensitizers of bacterial and human leukemic cells were carried out with these sensitizers, in comparison with HPD and Photofrin II. The new sensitizers were found to have high quantum yields for production of singlet oxygen in solutions. They also have comparable photosensitizing capacities of bacterial cells.
© (1992) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Benjamin Ehrenberg, Benjamin Ehrenberg, Adina Lavi, Adina Lavi, Yeshayahu Nitzan, Yeshayahu Nitzan, Zvi Malik, Zvi Malik, Hava Ladan, Hava Ladan, Fred M. Johnson, Fred M. Johnson, Jonathan L. Sessler, Jonathan L. Sessler, } "Spectroscopy, photokinetics, and cellular effect of far-red and near-infrared absorbing photosensitizers", Proc. SPIE 1645, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy, (1 June 1992); doi: 10.1117/12.60947; https://doi.org/10.1117/12.60947
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