Three new phthalocyanines with potential for PDT studies

Boris D. Rihter; Maria D. Bohorquez; Michael A. J. Rodgers; Malcolm E. Kenney

doi:10.1117/12.60946

1 June 1992 Three new phthalocyanines with potential for PDT studies

Boris D. Rihter, Maria D. Bohorquez, Michael A. J. Rodgers, Malcolm E. Kenney

Proceedings Volume 1645, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy; (1992) https://doi.org/10.1117/12.60946
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

The synthesis and characterization of a tetradibenzobarrelenoocta-n-butoxyzinc phthalocyanine, as well as the phthalocyanines t-butyldimethylsiloxy-N(3(beta) -acetoxy-23, 24-dinor-5-cholenoyl)-4-amino-n-butyldimethylsiloxysilicon phthalocyanine and bis- N(3(beta) -acetoxy-23,24-dinor-5-cholenoyl)-4-amino-n-butyldimethylsiloxysilicon phthalocyanine are reported. The zinc phthalocyanine is soluble, open at its center and highly hindered. It has a deep red absorption and a long triplet state lifetime. The silicon phthalocyanines have red absorptions and ligands bearing functions that have a resemblance to a part of the core of the low density lipoprotein fraction of blood serum. The zinc phthalocyanine has the potential to be a good photosensitizer, and the silicon phthalocyanines or related compounds have the potential to be preferentially accumulated by tumor cells. All three compounds are of interest for photodynamic therapy studies.

Citation Download Citation

Boris D. Rihter, Maria D. Bohorquez, Michael A. J. Rodgers, and Malcolm E. Kenney "Three new phthalocyanines with potential for PDT studies", Proc. SPIE 1645, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy, (1 June 1992); https://doi.org/10.1117/12.60946

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available