Paper
7 August 1992 Improvements in the accuracy and statistical variance of the Monte Carlo simulation of light distribution in tissue
Craig M. Gardner, Ashley J. Welch
Author Affiliations +
Proceedings Volume 1646, Laser-Tissue Interaction III; (1992) https://doi.org/10.1117/12.137485
Event: OE/LASE '92, 1992, Los Angeles, CA, United States
Abstract
Monte Carlo simulations provide accurate descriptions of light distribution in complex geometry, multiple layer tissues at the expense of long computation times. In addition, the accuracy of the light distribution quantity calculated is influenced by the resolution of the simulation if spatial convolution is used. A method of increasing the accuracy of the calculated fluence rate without increasing computation time is to consider the Beer-Lambert law source attenuation in the tissue analytically, separate from the Monte Carlo numeric calculation of the remaining multiple scattering process. A method of reducing the time of computation needed for a desired maximum statistical variance is to use a non-linear grid that provides high resolution in areas of interest and lower resolution far away from the source and boundaries. The theory of the source attenuation function is discussed. Results demonstrating the validity of the analytic function and the use of non-linear grids are provided and compared to standard Monte Carlo techniques.
© (1992) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Craig M. Gardner and Ashley J. Welch "Improvements in the accuracy and statistical variance of the Monte Carlo simulation of light distribution in tissue", Proc. SPIE 1646, Laser-Tissue Interaction III, (7 August 1992); https://doi.org/10.1117/12.137485
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Cited by 7 scholarly publications.
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KEYWORDS
Monte Carlo methods

Absorption

Point spread functions

Tissue optics

Signal attenuation

Convolution

Tissues

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