Comparison of bare fiber and contact diffuser tip inductions of interstitial laser lesions: assessment of reproducibility using magnetic resonance imaging

Keyvan Farahani; Dan J. Castro; Robert B. Lufkin

doi:10.1117/12.137512

1 June 1992 Comparison of bare fiber and contact diffuser tip inductions of interstitial laser lesions: assessment of reproducibility using magnetic resonance imaging

Keyvan Farahani, Dan J. Castro, Robert B. Lufkin

Author Affiliations +

Proceedings Volume 1650, Medical Lasers and Systems; (1992) https://doi.org/10.1117/12.137512
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

Ninety interstitial lesions were produced in ex-vivo sheep liver using various power outputs (5, 10, and 20 Watts) and exposure times for delivery of 200 Joules of the Nd:YAG laser energy. For the purpose of determining lesion reproducibility, two different methods of laser energy delivery to tissue, namely, the bare fiber optic and the sapphire diffuser tip techniques, were utilized. Cross-sectional magnetic resonance imaging (MRI) or laser treated specimens were performed on a 1.5 Tesla superconducting magnet. Images were examined for shape and extent of damage, as well as uniformity. Lateral and longitudinal extent of thermal injury was measured from the image of each lesion. Results showed that the diffuser tip method is better able to reproduce lesions than the bare fiber method, particularly when high levels of laser power are employed. This study indicates the need for development of MRI-compatible diffuser tip technology for use in MRI-guided interstitial laser therapy.

Citation Download Citation

Keyvan Farahani, Dan J. Castro, and Robert B. Lufkin "Comparison of bare fiber and contact diffuser tip inductions of interstitial laser lesions: assessment of reproducibility using magnetic resonance imaging", Proc. SPIE 1650, Medical Lasers and Systems, (1 June 1992); https://doi.org/10.1117/12.137512

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