1 June 1992 Validation of quantitative computed tomographic evaluation of bone mineral density of several CT scanners
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Abstract
We have validated a pre-existing model for QCT evaluation of bone mineral density by scanning a commercial bone mineral density phantom on several CT scanners and evaluating the accuracy and reproducibility of bone mineral density measurements on each. The model assumes that bone mineral density is a linear function of CT number of bone. Rather than imaging bone mineral density standards for calibration, we computed an `equivalent bone mineral density' for fat and muscle from the known linear relationship between bone mineral density and CT number to remove the dependence of bone mineral density on field non- uniformities caused by beam hardening and scattered radiation, positioning errors and quality control. The `equivalent bone mineral density' for fat and muscle were computed from spectral data and atomic composition of fat and tissue for a GE 9800 scanner. These were used to establish the true bone mineral density of two reference BMD standards used in the phantom and these in turn were used to measure the `equivalent bone mineral density' of fat and muscle on other CT scanners. Phantom measurements on several other CT scanners were used to compute the `equivalent bone mineral density' of the phantom inserts for those systems. Results from the Picker 1200, the Philips LX and the Siemens Somatom DR/H were compared with the results of the GE 9800.
© (1992) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Steven L. Fritz, Charles D. Stockham, "Validation of quantitative computed tomographic evaluation of bone mineral density of several CT scanners", Proc. SPIE 1652, Medical Imaging VI: Image Processing, (1 June 1992); doi: 10.1117/12.59438; https://doi.org/10.1117/12.59438
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