9 March 1993 Correlations between cadmium concentration in urine and exposure variables
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Abstract
As part of the study 'UMWELT und GESUNDHEIT 1985/86', a representative samples of the population of the Federal Republic of Germany was examined for urinary Cd. A log-linear prediction model based on 2109 cases led to an explained variance portion of R2 equals .32. Strong associations were revealed between urinary cadmium and the smoking history and age of the subjects. This is evidence of the function urinary cadmium has as an indicator of the Cd body burden. However, there are also clear connections with physiological parameters (urinary creatinine and serum urea), which are taken to be a modification of Cd excretion by renal function. The association between urinary Cd and serum urea can also be interpreted as a cadmium-induced renal dysfunction. Urinary Cd concentrations tend to be lower in regions with low industrial nitrogen oxide emissions and high economic dynamics, as well as in non- urban residential structures.
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Elmar Schwarz, Martina Chutsch, Christian M. Krause, Christine Schulz, Wolfgang Thefeld, "Correlations between cadmium concentration in urine and exposure variables", Proc. SPIE 1716, International Conference on Monitoring of Toxic Chemicals and Biomarkers, (9 March 1993); doi: 10.1117/12.140290; https://doi.org/10.1117/12.140290
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