Laser-based fiberoptic immunosensors

Tuan Vo-Dinh; Jean Pierre Alarie; Michael J. Sepaniak

doi:10.1117/12.140280

9 March 1993 Laser-based fiberoptic immunosensors

Tuan Vo-Dinh, Jean Pierre Alarie, Michael J. Sepaniak

Proceedings Volume 1716, International Conference on Monitoring of Toxic Chemicals and Biomarkers; (1993) https://doi.org/10.1117/12.140280
Event: Environmental Sensing '92, 1992, Berlin, Germany

Abstract

This paper provides a brief overview of the development and application of fiber-optic antibody-based fluoroimmunosensors (FIS) for measuring environmental pollutants and related biomarkers of human exposure and health effects. The FIS combines the excellent specificity of the antigen/antibody reaction, the high sensitivity of laser excitation, and the versatility of fiber-optics technology. Various types of FIS devices were also used to detect toxic chemicals (such as benzo-a-pyrene) and related DNA adducts (e.g., benzo(a)pyrene tetrol).

Citation Download Citation

Tuan Vo-Dinh, Jean Pierre Alarie, and Michael J. Sepaniak "Laser-based fiberoptic immunosensors", Proc. SPIE 1716, International Conference on Monitoring of Toxic Chemicals and Biomarkers, (9 March 1993); https://doi.org/10.1117/12.140280

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