Imaging microscopy with x-ray lasers at LLNL

Luiz Barroca Da Silva; James E. Trebes; Stanley Mrowka; Brian J. MacGowan; Jeffrey A. Koch; Dennis L. Matthews; Troy W. Barbee; Rod Balhorn; Joe W. Gray; Erik H. Anderson; D. Kern; David T. Attwood

doi:10.1117/12.138756

13 January 1993 Imaging microscopy with x-ray lasers at LLNL

Luiz Barroca Da Silva; James E. Trebes; Stanley Mrowka; Brian J. MacGowan; Jeffrey A. Koch; Dennis L. Matthews; Troy W. Barbee; Rod Balhorn; Joe W. Gray; Erik H. Anderson; D. Kern; David T. Attwood

Author Affiliations +

Proceedings Volume 1741, Soft X-Ray Microscopy; (1993) https://doi.org/10.1117/12.138756
Event: San Diego '92, 1992, San Diego, CA, United States

Abstract

Imaging microscopy with short pulse (200 ps) x-ray lasers offers the opportunity of high resolution three-dimensional imaging of specimens in an aqueous environment without the blurring effects associated with natural motion. As a first step toward this goal we have performed imaging experiments which clearly resolved 500 angstrom features on a gold test pattern. In addition, we have taken images of dried biological specimens as a basis for comparison in future wet specimen imaging. The results of these experiments are described. We also discuss some of the alignment problems involved in doing x-ray microscopy with low repetition rate systems where in situ focusing of the imaging optics is not practical as single shot exposures can alter the specimen.

Citation Download Citation

Luiz Barroca Da Silva, Luiz Barroca Da Silva, James E. Trebes, James E. Trebes, Stanley Mrowka, Stanley Mrowka, Brian J. MacGowan, Brian J. MacGowan, Jeffrey A. Koch, Jeffrey A. Koch, Dennis L. Matthews, Dennis L. Matthews, Troy W. Barbee, Troy W. Barbee, Rod Balhorn, Rod Balhorn, Joe W. Gray, Joe W. Gray, Erik H. Anderson, Erik H. Anderson, D. Kern, D. Kern, David T. Attwood, David T. Attwood, } "Imaging microscopy with x-ray lasers at LLNL", Proc. SPIE 1741, Soft X-Ray Microscopy, (13 January 1993); doi: 10.1117/12.138756; https://doi.org/10.1117/12.138756

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