Current and emerging high-speed applications and environments create new and challenging requirements for high-speed channels on large systems. The Fiber Channel Standard (FCS) defines transmission and signalling protocols that allow various Upper Level Protocols (for example, IPI3 and IP) to be transported over a variety of physical interfaces. This rich set of function allow FCS to address many aspects and varieties of high-speed interconnect, by permitting a variety of implementations, based on trade-offs of cost, performance objectives, implementation complexity, and recoverability. The current presentation describes several high-speed applications and environments and the usage of FCS channels by large systems in those environments. Application of various FCS functions and features to this large system environment are discussed.