30 April 1993 Ray-tracing determination of evanescent-wave penetration depth in tapered fiber optic probes
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Abstract
A fiber optic biosensor has been developed which monitors fluorescence to detect antibody/antigen binding within the evanescent wave. The sensing region is formed by removal of cladding from the core along the distal end of a step-index optical fiber and attaching the antibody. Reducing the radius by tapering the probe overcomes the mismatch in V-number which arises between the declad, immersed probe, and the clad fiber. Ray tracing analysis of tapered probes and of combination taper probes demonstrates that the evanescent wave penetration depth increases along the length of the taper, creating a probe with increased excitation light available at the surface for stimulating fluorescence.
© (1993) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Joel P. Golden, Joel P. Golden, Sina Y. Rabbany, Sina Y. Rabbany, George P. Anderson, George P. Anderson, "Ray-tracing determination of evanescent-wave penetration depth in tapered fiber optic probes", Proc. SPIE 1796, Chemical, Biochemical, and Environmental Fiber Sensors IV, (30 April 1993); doi: 10.1117/12.143504; https://doi.org/10.1117/12.143504
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