Paper
22 September 1992 Edge information at landmarks in medical images
Fred L. Bookstein, William D. K. Green
Author Affiliations +
Proceedings Volume 1808, Visualization in Biomedical Computing '92; (1992) https://doi.org/10.1117/12.131082
Event: Visualization in Biomedical Computing, 1992, Chapel Hill, NC, United States
Abstract
In many current medical applications of image analysis, objects are detected and delimited by boundary curves or surfaces. Yet the most effective multivariate statistics available pertain to labelled points (`landmarks') only. In the finite-dimensional feature space that landmarks support, each case of a data set is equivalent to a deformation map deriving it from the average form. This paper reviews a recent extension of a spline-based approach so as to incorporate edge information, and extends it further to apply to images that incorporate landmarks. In this implementation, edgels are restricted to landmark loci: they are interpreted as pairs of landmarks at infinitesimal separation in a specific direction. To shears of these infinitesimal edgels correspond well-defined incremental deformations of the entire image. There results a very flexible new strategy for normalizing the geometry of a specimen scene before representing its grey levels as functions of position. Applications of this strategy will include more powerful approaches to picture averaging and more precise visualizations of biological processes that affect the shapes of medical images, their content, or both.
© (1992) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Fred L. Bookstein and William D. K. Green "Edge information at landmarks in medical images", Proc. SPIE 1808, Visualization in Biomedical Computing '92, (22 September 1992); https://doi.org/10.1117/12.131082
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CITATIONS
Cited by 26 scholarly publications.
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KEYWORDS
Visualization

Medical imaging

Biomedical optics

Image analysis

Biological research

Image processing

Statistical analysis

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